Imine-based multicomponent polymerization: Concepts, structural diversity and applications

Multicomponent reactions (MCRs) are remarkable one-pot combinatorial synthetic tools involving at least three reactants whose nearly all atoms incorporated in the final product. The development of these high atom-efficient considerably raised level molecular complexity and diversity last decades. Nowadays, MCRs no longer confined to organic synthesis have seen their use extended polymer science. latter tend occupy an increasingly important place sustain eager demand for innovative structurally diverse macromolecules involved highly valued applications. While MRCs can serve monomer post-polymerization modification, they offer full potential step-growth polymerizations, namely multicomponent polymerizations (MCPs). This review provides a comprehensive up date overview imine-based MCPs highlights great design advanced linear, hyperbranched crosslinked polymers. focus is placed on imines, most common valuable MCRs’ intermediates which prone various nucleophilic attacks give access variety products. efficiency, feature, substrates versatility limitations as well discussed detail. Some also be combined afford unique complex structures. At this stage, several already mature enough cutting-edge applications biomedicine, energy, environment catalysis amongst others. existing challenges addressed identified future research directions accordingly. MCPs, particular ones, will undoubtedly further grow confirm status essential macromolecular engineering future.